How Cryo-EM Became so Hot.

Cheng, Yifan; Glaeser, Robert M; Nogales, Eva · Cell · 2017

editorial · Level V

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Abstract

The Royal Swedish Academy of Sciences awarded the 2017 Nobel Prize for Chemistry to Jacques Dubochet, Joachim Frank, and Richard Henderson for "developing cryoelectron microscopy for the high-resolution structure determination of biomolecules in solution." Achieving this goal, which required innovation, persistence, and uncommon physical insight, has broadened horizons for structural studies in molecular and cell biology.

Medical subject headings