Platelets, On Your Marks, Get Set, Migrate!
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 29195072.
- Also identified by DOI 10.1016/j.cell.2017.11.026.
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Abstract
The idea that anucleate platelets display autonomous migration has long been viewed with skepticism. Gaertner et al. provide in vivo evidence that platelets undergo active migration at sites of thrombus formation and in inflamed liver sinusoids. Integrin-dependent migration allows platelets to scavenge and bundle fibrin-bound material, including intravascular bacteria.
Medical subject headings
- Blood Platelets
- Thrombosis