Editorial Commentary: The Acrid Bioscrew in Anterior Cruciate Ligament Reconstruction of the Knee.

Abstract

Bioresorbable screws have been widely adopted for graft fixation in knee anterior cruciate ligament (ACL) reconstruction on the promise of screw resorbtion and replacement by bone. When considering the value of bioresorbable screws, it is imperative to understand that the "A" in PGA and PLA, the base ingredient of all bioscrews, is for Acid. All resorb by a process of hydrolysis; the speed and extent of resorbtion is determined by both the acidity of the screw and the environment in which it is placed. Regrettably, the promise of reliable, predictable screw resorbtion and replacement by bone remains elusive, despite the addition of "osteoconductive" materials. For the most part, bioresorbables are associated with good clinical outcomes for ACL reconstruction; they are not "dangerous," just disappointing with respect to bony replacement. We propose that nonresorbing inert plastics such as PEEK (polyether ether ketone) may be better suited for the purpose of graft fixation devices for ACL reconstruction.