Key Factors Influencing the Emergence of Human Immunodeficiency Virus Drug Resistance in Low- and Middle-Income Countries.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 29207000.
- Also identified by DOI 10.1093/infdis/jix409 and PMC identifier 5853971.
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Abstract
The emergence and spread of human immunodeficiency virus (HIV) drug resistance from antiretroviral roll-out programs remain a threat to long-term control of the HIV-AIDS epidemic in low- and middle-income countries (LMICs). The patterns of drug resistance and factors driving emergence of resistance are complex and multifactorial. The key drivers of drug resistance in LMICs are reviewed here, and recommendations are made to limit their influence on antiretroviral therapy efficacy.
Medical subject headings
- Anti-HIV Agents
- HIV
- HIV Infections