RevAMPing Mitochondrial Shape to Live Longer.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 29211978.
- Also identified by DOI 10.1016/j.cmet.2017.11.010.
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Abstract
Whether and how mitochondria connect reduced energy intake to healthy aging are unclear. In this issue of Cell Metabolism, Weir et al. (2017) find that constitutive AMPK activation and dietary restriction promote longevity in C. elegans via remodeling of the mitochondrial network and fatty acid oxidation in peripheral tissues.
Medical subject headings
- Caenorhabditis elegans Proteins
- Longevity