Susceptibility of HLA-E*01:03 Allele Carriers to Develop Cytomegalovirus Replication After Living-Donor Kidney Transplantation.

Guberina, Hana; da Silva Nardi, Fabiola; Michita, Rafael Tomoya; Dolff, Sebastian; Bienholz, Anja; Heinemann, Falko M; Wilde, Benjamin; Trilling, Mirko et al. · J Infect Dis · 2018

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Abstract

Cytomegalovirus (CMV) causes serious complications among solid organ transplant recipients. We report the positive correlation between the presence of the HLA-E*01:03 allele in living-donor kidney recipients and CMV reactivation during the first year after transplantation. Thus, HLA-E genotyping may help identify CMV replication-prone patients who require individualized patient-based CMV management.

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