Organoids required! A new path to understanding human brain development and disease.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 29298289.
- Also identified by DOI 10.1038/nmeth.4557.
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Abstract
Our ability to study the developing human brain has recently been dramatically advanced by the development of human 'brain organoids', three-dimensional culture systems that recapitulate selected aspects of human brain development in reductionist, yet complex, tissues in vitro. Here I discuss the promises and challenges this new model system presents.
Medical subject headings
- Brain
- Brain Diseases
- Organogenesis
- Organoids
- Pluripotent Stem Cells