Chewing through Roots: How Leukemia Invades and Disrupts the Bone Marrow Microenvironment.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 29304342.
- Also identified by DOI 10.1016/j.stem.2017.12.014.
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Abstract
The bone marrow (BM) niche is a complex microenvironment that supports healthy hematopoietic stem cells (HSCs) throughout life. In this issue of Cell Stem Cell, Duarte et al. (2018) reveal the spatio-temporal progress of leukemic cells as they invade and occupy the niche, ultimately outcompeting native HSCs.
Medical subject headings
- Bone Marrow
- Stem Cell Niche