Outcomes of Surgical Ligation after Unsuccessful Pharmacotherapy for Patent Ductus Arteriosus in Neonates Born Extremely Preterm.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 29306492.
- Also identified by DOI 10.1016/j.jpeds.2017.11.029.
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Abstract
A retrospective cohort study of neonates born extremely preterm with persistent patent ductus arteriosus after unsuccessful pharmacologic closure compared outcomes between 166 surgically ligated and 142 nonligated neonates. After adjustment for confounders, ligation was not associated with the composite outcome of death or neurodevelopmental impairment, neurodevelopmental impairment alone, chronic lung disease, or retinopathy of prematurity among survivors.
Medical subject headings
- Anti-Inflammatory Agents, Non-Steroidal
- Ductus Arteriosus, Patent
- Infant, Extremely Premature
- Infant, Premature, Diseases