GIGGLE: a search engine for large-scale integrated genome analysis.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 29309061.
- Also identified by DOI 10.1038/nmeth.4556 and PMC identifier 5872823.
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Abstract
GIGGLE is a genomics search engine that identifies and ranks the significance of genomic loci shared between query features and thousands of genome interval files. GIGGLE (https://github.com/ryanlayer/giggle) scales to billions of intervals and is over three orders of magnitude faster than existing methods. Its speed extends the accessibility and utility of resources such as ENCODE, Roadmap Epigenomics, and GTEx by facilitating data integration and hypothesis generation.
Medical subject headings
- Breast Neoplasms
- Genome, Human
- Genomics
- Search Engine
- Sequence Analysis, DNA
- Software