Investigation of quercetin and hyperoside as senolytics in adult human endothelial cells.
basic_science · Level V
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- Record sourced from PubMed, PMID 29315311.
- Also identified by DOI 10.1371/journal.pone.0190374 and PMC identifier 5760026.
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Abstract
Previously, quercetin has been reported to be a senolytic, a drug that selectively removes senescent cells, in HUVECs. However, we found neither quercetin nor Q3G was effective as a senolytic for adult human endothelial cells.
Medical subject headings
- Cellular Senescence
- Endothelium, Vascular
- Quercetin