Apoptotic Regulatory T Cells Retain Suppressive Function through Adenosine.
Level V
Where this comes from
- Record sourced from PubMed, PMID 29320710.
- Also identified by DOI 10.1016/j.cmet.2017.12.013.
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Abstract
Regulatory T cells maintain tolerance and prevent autoimmunity, but their suppressive effects can hinder immune responses against cancer. In Nature Immunology, Maj et al., 2017 report that regulatory T cells can execute these actions through the nucleoside adenosine even after cell death.
Medical subject headings
- Neoplasms
- T-Lymphocytes, Regulatory