EMT in cancer.
expert_opinion · Level V
Where this comes from
- Record sourced from PubMed, PMID 29326430.
- Also identified by DOI 10.1038/nrc.2017.118.
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Abstract
Similar to embryonic development, changes in cell phenotypes defined as an epithelial to mesenchymal transition (EMT) have been shown to play a role in the tumorigenic process. Although the first description of EMT in cancer was in cell cultures, evidence for its role in vivo is now widely reported but also actively debated. Moreover, current research has exemplified just how complex this phenomenon is in cancer, leaving many exciting, open questions for researchers to answer in the future. With these points in mind, we asked four scientists for their opinions on the role of EMT in cancer and the challenges faced by scientists working in this fast-moving field.
Medical subject headings
- Epithelial-Mesenchymal Transition
- Neoplasms