Weaving New Insights for the Genetic Regulation of Human Cognitive Phenotypes.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 29328907.
- Also identified by DOI 10.1016/j.cell.2017.12.037.
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Abstract
Psychiatric genetic studies have drawn associations between human cognitive traits and noncoding genomic variants. However, the mechanistic effects of these variants are unclear. By weaving in strands of genomic data from developing human brains, de la Torre-Ubieta et al. tie disease-associated loci to functional enhancers, target genes, and putatively affected cell types.
Medical subject headings
- Chromatin
- Genome-Wide Association Study