A Viral (Arc)hive for Metazoan Memory.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 29328922.
- Also identified by DOI 10.1016/j.cell.2017.12.029.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Arc, a master regulator of synaptic plasticity, contains sequence elements that are evolutionarily related to retrotransposon Gag genes. Two related papers in this issue of Cell show that Arc retains retroviral-like capsid-forming ability and can transmit mRNA between cells in the nervous system, a process that may be important for synaptic function.
Medical subject headings
- Gene Products, gag
- Presynaptic Terminals