Anti-angiogenic drug loaded liposomes: Nanotherapy for early atherosclerotic lesions in mice.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 29338009.
- Also identified by DOI 10.1371/journal.pone.0190540 and PMC identifier 5770017.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Fumagillin-loaded liposomes were injected into ApoE-KO mice. The animals were divided into several groups to test the efficacy of this anti-angiogenic drug for early treatment of atherosclerotic lesions. Statistical analysis of the lesions revealed a decrease in the lesion size after 5 weeks of treatment.
Medical subject headings
- Angiogenesis Inhibitors
- Atherosclerosis
- Cyclohexanes
- Disease Models, Animal
- Drug Carriers
- Fatty Acids, Unsaturated
- Liposomes
- Nanoparticles