Ectopic Cushing's syndrome secondary to olfactory neuroblastoma.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 29340776.
- Also identified by DOI 10.1007/s00701-017-3447-y and PMC identifier 5897482.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
We present the case of a patient with Cushing's syndrome secondary to ectopic ACTH secretion. A MR of the head showed a left-sided nasal mass extending down from the cribriform plate. The patient underwent endoscopic resection with nearly complete removal of the mass. Histological examination showed an ACTH-secreting olfactory neuroblastoma (ONB). The patient's cortisol levels returned to normal range after surgery and have remained normal for over a year. ONB is a rare cause for ectopic ACTH secretion. This case highlights the diagnostic and management difficulties in patients with ectopic ACTH secretion, and provides a brief review of ONB.
Medical subject headings
- Cushing Syndrome
- Esthesioneuroblastoma, Olfactory
- Nose Neoplasms