Engineering precision biomaterials for personalized medicine.

Aguado, Brian A; Grim, Joseph C; Rosales, Adrianne M; Watson-Capps, Jana J; Anseth, Kristi S · Sci Transl Med · 2018

review · Level V

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Abstract

As the demand for precision medicine continues to rise, the "one-size-fits-all" approach to designing medical devices and therapies is becoming increasingly outdated. Biomaterials have considerable potential for transforming precision medicine, but individual patient complexity often necessitates integrating multiple functions into a single device to successfully tailor personalized therapies. Here, we introduce an engineering strategy based on unit operations to provide a unified vocabulary and contextual framework to aid the design of biomaterial-based devices and accelerate their translation.

Medical subject headings