Oral Medications to Treat Toenail Fungal Infection.
systematic_review · Level I
Where this comes from
- Record sourced from PubMed, PMID 29362778.
- Also identified by DOI 10.1001/jama.2017.20160.
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Abstract
Which oral antifungal medication is associated with the highest clinical (ie, normal appearance of the toenail) and mycological (negative culture, microscopy, or both) cure rates vs placebo or other antifungals when used to treat fungal infections? Both terbinafine and azole-based medications were associated with higher clinical and mycological cure rates compared with placebo (high-quality evidence). Azoles were associated with lower cure rates than terbinafine when compared directly.
Medical subject headings
- Antifungal Agents
- Azoles
- Foot Dermatoses
- Naphthalenes
- Onychomycosis
Anatomy
- foot