Meiotic Recombination: Genetics' Good Old Scalpel.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 29373827.
- Also identified by DOI 10.1016/j.cell.2018.01.017.
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Abstract
In the era of genome engineering, a new study returns to classical genetics to decipher genotype-phenotype relationships in unprecedented throughput and with unprecedented accuracy. Capitalizing on natural variation in yeast strains and frequent meiotic recombination, She and Jarosz (2018) dissect and map to nucleotide resolution, simple and complex determinants of diverse phenotypic traits.
Medical subject headings
- Nucleotides
- Saccharomyces cerevisiae