Small-Cell Neuroendocrine Tumors: Cell State Trumps the Oncogenic Driver.

Oser, Matthew G; Jänne, Pasi A · Clin Cancer Res · 2018

editorial · Level V

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Abstract

Small-cell neuroendocrine cancers often originate in the lung but can also arise in the bladder or prostate. Phenotypically, small-cell carcinoma of the bladder (SCCB) shares many similarities with small-cell lung cancer (SCLC). It is unknown whether SCCB and SCLC share common genetic driver mutations. <i>Clin Cancer Res; 24(8); 1775-6. ©2018 AACR</i><i>See related article by Chang et al., p. 1965</i>.

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