Measurement of Human Immunodeficiency Virus p24 Antigen in Human Cerebrospinal Fluid With Digital Enzyme-Linked Immunosorbent Assay and Association With Decreased Neuropsychological Performance.

Anderson, Albert M; Tyor, William R; Mulligan, Mark J; Waldrop-Valverde, Drenna; Lennox, Jeffrey L; Letendre, Scott L · Clin Infect Dis · 2018

case_series · Level IV

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Abstract

New tools are needed to understand human immunodeficiency virus central nervous system involvement. Testing 15 cerebrospinal fluid (CSF) samples for p24 antigen, using a high-sensitivity assay, we found a strong correlation trend between CSF p24 concentration and worse neuropsychological performance.

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