Metastasis Seeding Cells: Lone Invaders or Mass Migrators?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 29386220.
- Also identified by DOI 10.1158/1078-0432.CCR-17-3644 and PMC identifier 5933519.
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Abstract
Lymph node metastases are among the best predictors of recurrence and of cancer-related death in early-stage colorectal cancers. Yet, despite their clinical and biological relevance, it remains elusive how lymph node metastases develop and whether metastatic seeding is a major bottleneck that restrains genetic heterogeneity of metastatic disease. <i>Clin Cancer Res; 24(9); 2032-4. ©2018 AACR</i><i>See related article by Ulintz et al., p. 2214</i>.
Medical subject headings
- Colonic Neoplasms
- Colorectal Neoplasms