Shaping the Pluripotent Genome: Switches, Borders, and Loops.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 29395051.
- Also identified by DOI 10.1016/j.stem.2018.01.005.
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Abstract
Three-dimensional genome organization is largely cell type specific and requires reorganization during cell fate transitions. A recent study in Nature Genetics (Stadhouders et al., 2018) offers important insights into the principles and drivers of such reorganization during reprogramming of somatic cells into pluripotent stem cells.
Medical subject headings
- Cellular Reprogramming
- Transcription Factors