RNA Editing: Unexplored Opportunities in the Cardiovascular System.

Uchida, Shizuka; Jones, Steven P · Circ Res · 2018

review · Level V

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Abstract

Increasing usage of next generation sequencing (NGS) technology will illuminate the extent of RNA modifications, which may affect various pathophysiological conditions. Here, we will highlight one such category of RNA modification called “RNA editing”, which can be detected from RNA sequencing (RNA-seq) data by simply modifying the data analysis pipeline using bioinformatics methods.

Medical subject headings