Brother's Keeper: Wild-Type Mutant K-Ras Dimers Limit Oncogenesis.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 29425486.
- Also identified by DOI 10.1016/j.cell.2018.01.019.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
K-Ras is the undisputed champion of oncogenes, yet our ability to interfere with its oncogenic function is hampered by insufficient mechanistic understanding. In this issue of Cell, Ambrogio and colleagues connect the ability of K-Ras to dimerize to the ability of wild-type K-Ras to limit the oncogenic properties of the mutant.
Medical subject headings
- Proto-Oncogene Proteins p21(ras)
- Siblings