Exogenous human herpesvirus 6 reinfection after tumor-infiltrating T-lymphocyte therapy.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 29434005.
- Also identified by DOI 10.1016/j.jcyt.2017.12.006.
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Abstract
Exogenous human herpes virus 6 (HHV-6) reinfection has never been reported in patients receiving tumor-infiltrating T lymphocytes therapy. We report an unusual case of HHV-6 infection following infusion of HHV-6 infected autologous T lymphocytes. HHV-6 infection could interfere with the tumor antigen immune recognition and the efficacy of immunotherapy.
Medical subject headings
- Herpesvirus 6, Human
- Immunotherapy, Adoptive
- Lymphocytes, Tumor-Infiltrating
- Melanoma
- Roseolovirus Infections
- Skin Neoplasms