KMgene: a unified R package for gene-based association analysis for complex traits.
Level V
Where this comes from
- Record sourced from PubMed, PMID 29438558.
- Also identified by DOI 10.1093/bioinformatics/bty066 and PMC identifier 6246171.
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Abstract
SUMMARY: In this report, we introduce an R package KMgene for performing gene-based association tests for familial, multivariate or longitudinal traits using kernel machine (KM) regression under a generalized linear mixed model framework. Extensive simulations were performed to evaluate the validity of the approaches implemented in KMgene. AVAILABILITY AND IMPLEMENTATION: http://cran.r-project.org/web/packages/KMgene. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
Medical subject headings
- Genetic Testing
- Linear Models
- Multifactorial Inheritance
- Software