Detection of human bocavirus in Saudi healthy blood donors.
cross_sectional · Level IV
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- Record sourced from PubMed, PMID 29489915.
- Also identified by DOI 10.1371/journal.pone.0193594 and PMC identifier 5831472.
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Abstract
Human bocavirus is associated with respiratory disease worldwide, mainly in children. There are conflicting results, however, regarding the existence of the HBoV in blood donors. Three hundred whole blood samples from non-immunodeficient healthy blood donors were screened for the presence of HBoV by polymerase chain reaction. The HBoV genotype of positive samples was determined using direct gene sequencing. Twenty-one out of the three hundred blood samples were found to be positive for HBoV. Sequence analysis of the positive samples revealed that all the strains were related to the HBoV-1 type with a low rate of variation among the detected sequences. It was concluded that there is a considerable risk of contracting HBoV from a blood transfusion from normal healthy individuals.
Medical subject headings
- Blood Donors
- Healthy Volunteers
- Human bocavirus