<i>HER2</i> Deregulation in Lung Cancer: Right Time to Adopt an Orphan?

Cappuzzo, Federico; Landi, Lorenza · Clin Cancer Res · 2018

editorial · Level V

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Abstract

<i>HER2</i>-deregulated non-small cell lung cancer is an orphan of any specific therapy, probably because of lack of both accurate patient selection and effective drugs. Recent evidence suggests that osimertinib could be effective in <i>HER2</i>-amplified or mutated lung cancer as a single agent or in combination. <i>Clin Cancer Res; 24(11); 2470-2. ©2018 AACR</i><i>See related article by Liu et al., p. 2594</i>.

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