Living Up to the Hype: Protein Synthesis Promotes Hypertranscription in Embryonic Stem Cells.
editorial · Level V
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- Record sourced from PubMed, PMID 29499142.
- Also identified by DOI 10.1016/j.stem.2018.02.008.
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Abstract
The rapid proliferation and unlimited self-renewal of embryonic stem cells depends upon a permissive chromatin landscape that enables hypertranscription. In this issue of Cell Stem Cell, Bulut-Karslioglu et al. report that euchromatin and transcriptional output are enhanced by protein synthesis in embryonic stem cells (Bulut-Karslioglu et al., 2018).
Medical subject headings
- Chromatin
- Embryonic Stem Cells