Reversing Time: Ezh1 Deficiency Hastens Definitive Hematopoiesis.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 29499144.
- Also identified by DOI 10.1016/j.stem.2018.02.006.
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Abstract
The inability to derive multipotent hematopoietic stem cells in vitro stems in part from a limited understanding of how multipotency is acquired during development. Recently in Nature,Vo et al. (2018) reveal the epigenetic enzyme Ezh1 as a master regulator of multipotency during hematopoietic stem cell development.
Medical subject headings
- Hematopoiesis
- Hematopoietic Stem Cells