Paracetamol Serum Concentrations in Neonates Treated Enterally for Ductal Closure: A Pilot Study.

Bin-Nun, Alona; Fink, Daniel; Mimouni, Francis B; Algur, Nurit; Hammerman, Cathy · J Pediatr · 2018

case_series · Level IV

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Abstract

We determined serum paracetamol concentrations 4 hours after the eighth dose in infants treated enterally for ductal closure. Serum paracetamol concentrations correlated (P = .0026) with ductal response. No patent ductus arteriosus in a baby with paracetamol levels <20 mg/L closed in response to treatment. Paracetamol levels also correlated (P = .046) with postnatal age.

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