Prolonged Detection of Zika Virus Nucleic Acid Among Symptomatic Pregnant Women: A Cohort Study.

Lozier, Matthew J; Rosenberg, Eli S; Doyle, Kate; Adams, Laura; Klein, Liore; Muñoz-Jordan, Jorge; Alvarado, Luisa I; Sharp, Tyler M et al. · Clin Infect Dis · 2018

prospective_cohort · Level II

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Abstract

A prospective cohort of women with reverse transcription polymerase chain reaction (RT-PCR) confirmed Zika virus infection aged 18-39 years in Puerto Rico found that pregnant women have about a 3-fold longer estimated median detection of Zika virus RNA in serum, which can increase definitive diagnosis of infection and facilitate timely and appropriate clinical management.

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