A case report of rapid-onset hyponatremia induced by low-dose olanzapine.

Anil, Sethulakshmi Sreevalsam; Ratnakaran, Badr; Suresh, Nisha · J Family Med Prim Care · 2017

case_report · Level V

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Abstract

Hyponatremia has been reported with the use of psychotropic drugs. Olanzapine does not find much mention as a cause of hyponatremia in literature; however, it has been found to be the second most frequently reported atypical antipsychotic to cause it. We report a case of hyponatremia due to syndrome of inappropriate antidiuretic hormone secretion which occurred at a rapid onset following the administration of low-dose olanzapine during inpatient treatment of a patient with bipolar disorder. We would like to highlight our case for the need to be vigil about such fatal side complications apart from metabolic side effects of atypical antipsychotics.