SnapShot: CGAS-STING Signaling.

Galluzzi, Lorenzo; Vanpouille-Box, Claire; Bakhoum, Samuel F; Demaria, Sandra · Cell · 2018

basic_science · Level V

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Abstract

CGAS responds to cytosolic DNA by initiating a STING-dependent response that ultimately engages innate immune effectors to ensure the preservation of organismal homeostasis.

Medical subject headings