Graft-Versus-Tumor Effect in Adenocarcinoma of the Lung.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 29571344.
- Also identified by DOI 10.1016/j.athoracsur.2017.11.002.
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Abstract
Donor T cells after allogeneic hematopoietic cell transplantation can give rise to the graft-versus-tumor (GVT) effect in hematologic malignancies. GVT effect has been reported previously to cause regression of some solid tumors. However, none have reported a documented case of GVT effect leading to complete resolution of adenocarcinoma of the lung. Here, we present the case of complete regression of a pathologically proven adenocarcinoma of the lung in a patient undergoing myeloablative-matched unrelated donor peripheral blood stem cell transplantation for the treatment of acute myelogenous leukemia.
Medical subject headings
- Adenocarcinoma
- Hematopoietic Stem Cell Transplantation
- Leukemia, Myeloid, Acute
- Lung Neoplasms