The Long Neglected Player: Modeling Tumor Uptake to Guide Optimal Dosing.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 29581133.
- Also identified by DOI 10.1158/1078-0432.CCR-18-0580.
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Abstract
Pharmacokinetic modeling, traditionally using drug exposure, is widely used to support decision-making in translational medicine and patient care. The development of mechanistic computational models that integrate drug concentrations at the site of action making use of existing knowledge opens a new paradigm in optimal dosing. <i>Clin Cancer Res; 24(14); 3236-8. ©2018 AACR</i><i>See related article by Ribba et al., p. 3325</i>.
Medical subject headings
- Neoplasms