Without Adaptive Immunity, There's a Cost to Responding STAT.

Brown, Eric M; Xavier, Ramnik J · Cell Metab · 2018

editorial · Level V

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Abstract

The relative contributions of innate and adaptive immune mechanisms in responding to the intestinal microbiota during ontogeny are largely unknown. A recent study in Nature by Mao et al. (2018) elegantly dissects the role of each cell type in the intestine and further describes the metabolic cost to innate immunity.

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