Editorial Commentary: Not All Bone Marrow Aspirate Concentrates Are the Same: The Necessity of Detailed Reporting and Other Lessons Learned From Cell-based Treatments in Orthopaedics.

Abstract

Bone marrow aspirate concentrates have become a popular therapeutic approach for several musculoskeletal conditions. A plethora of different preparations exist that make difficult to evaluate their clinical outcome and, thus, to make safe conclusions for their effectiveness. The first step for this assessment is comprehensive and reliable reporting of all the important variables that would allow characterization of their content and properties. This is critical for the understanding of their mechanism of action and the identification of the proper indications based on patient and disorder characteristics that could potentially lead to their effective application in clinical scenarios.