De Novo DNA Methylation: Marking the Path from Stem Cell to Neural Fate.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 29625060.
- Also identified by DOI 10.1016/j.stem.2018.03.006.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
DNA methylation is an epigenetic mark that plays pivotal roles in gene regulation, but its functions in neural fate decisions are poorly understood. In this issue of Cell Stem Cell, Ziller et al. (2018) show that the de novo methyltransferase Dnmt3a ensures efficient generation of motor neurons from stem cells.
Medical subject headings
- DNA (Cytosine-5-)-Methyltransferases
- DNA Methylation