Orchestrating Ribosomal Subunit Coordination to Control Stem Cell Fate.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 29625061.
- Also identified by DOI 10.1016/j.stem.2018.03.019.
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Abstract
The mechanisms responsible for maintaining ribosomal component stoichiometry, which is critical during cell fate transitions, are currently not well understood. In this issue of Cell Stem Cell, Corsini et al. (2018) demonstrate that the transcription and splicing-associated factor HTATSF1 controls stem cell fate by coordinately regulating ribosomal protein and RNA production.
Medical subject headings
- Embryonic Stem Cells