The Rules of Successful Speed Dating Are Complex, Even for Super-Enhancers.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 29625064.
- Also identified by DOI 10.1016/j.stem.2018.03.001.
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Abstract
Super-enhancers (SEs) are important for regulating cell identity genes and oncogenes, but correctly assigning target genes to SEs is difficult. Recently in Cell Reports, Lopes Novo et al. (2018) map interactions between SEs and promoters and observe a significant rewiring of complex SE-promoter networks between different pluripotent states.
Medical subject headings
- Mouse Embryonic Stem Cells