Anaemia and red blood cell transfusion in intracranial neurosurgery: a comprehensive review.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 29661416.
- Also identified by DOI 10.1016/j.bja.2017.11.108.
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Abstract
Both anaemia and blood transfusion are associated with poor outcomes in the neurosurgical population. Based on the available literature, the optimal haemoglobin concentration for neurologically injured patients appears to be in the range of 9.0-10.0 g dl<sup>-1</sup>, although the individual risks and benefits should be weighed. Several perioperative blood conservation strategies have been used successfully in neurosurgery, including correction of anaemia and coagulopathy, use of antifibrinolytics, and intraoperative cell salvage. Avoidance of non-steroidal anti-inflammatory drugs and starch-containing solutions is recommended given the potential for platelet dysfunction.
Medical subject headings
- Anemia
- Erythrocyte Transfusion
- Neurosurgical Procedures
- Perioperative Care