Glucagon-like peptide 1 receptor signaling attenuates respiratory syncytial virus-induced type 2 responses and immunopathology.
Level V
Where this comes from
- Record sourced from PubMed, PMID 29678751.
- Also identified by DOI 10.1016/j.jaci.2018.01.053 and PMC identifier 6078807.
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Abstract
GLP-1R signaling, an emerging anti-inflammatory therapeutic 59 target, 60 attenuated type 2-associated immunopathology in mice infected with a strain of RSV that was 61 isolated from a hospitalized infant with severe lower respiratory tract infection and bronchiolitis.
Medical subject headings
- Glucagon-Like Peptide-1 Receptor
- Hypoglycemic Agents
- Liraglutide
- Respiratory Syncytial Virus Infections
- Respiratory Syncytial Viruses
- Th2 Cells