Asparagine and Glutamine: Co-conspirators Fueling Metastasis.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 29719230.
- Also identified by DOI 10.1016/j.cmet.2018.04.012.
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Abstract
Cancer cells frequently hijack normal metabolic pathways to promote their growth and metastasis. Two recent papers by Knott et al. (2018) and Pavlova et al. (2018) demonstrate that asparagine and glutamine work in concert to drive tumor growth and metastasis through modulation of cell survival, growth, and EMT regulatory pathways.
Medical subject headings
- Asparagine
- Breast Neoplasms