ER stress in prostate cancer: A therapeutically exploitable vulnerability?
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 29720450.
- Also identified by DOI 10.1126/scitranslmed.aat3975.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Cooperative oncogenic effects resulting from the loss of PTEN and overexpression of MYC overcome the deleterious effects of endoplasmic reticulum stress not only to promote the growth of aggressive prostate cancer but also to expose a new therapy target for this disease (Nguyen <i>et al</i>, this issue).
Medical subject headings
- Endoplasmic Reticulum Stress
- Prostatic Neoplasms