Chemistry Takes Center Stage for Identifying Cancer Targetability.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 29727668.
- Also identified by DOI 10.1016/j.cell.2018.04.020.
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Abstract
Matching genetically defined cancer states to drugs that specifically target these states is a principal goal of personalized oncology medicine. In this issue, McMillan et al. show how large-scale chemical screening coupled to deep molecular profiling can identify mechanistically diverse druggable vulnerabilities for genetic subtypes of lung cancers.
Medical subject headings
- Gene Expression Profiling
- Lung Neoplasms