(IR)Factor for NAIP Expression.
editorial · Level V
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- Record sourced from PubMed, PMID 29727669.
- Also identified by DOI 10.1016/j.cell.2018.04.022.
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Abstract
IRF8 is a master transcription factor for immune cell development. In this issue, Karki et al. reveal that IRF8 governs the constitutive expression of genes encoding for NAIP proteins that are critical for the innate immune sensing of bacteria.
Medical subject headings
- Inflammasomes
- Neuronal Apoptosis-Inhibitory Protein