Patient-Derived iPSC-Hypothamic Neurons: The Ultimate Protocol.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 29727675.
- Also identified by DOI 10.1016/j.stem.2018.04.019.
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Abstract
Several methods for making hypothalamic-like neurons (iHTNs) from human or mouse induced pluripotent stem cells (iPSCs) with varying efficiencies exist. In this issue of Cell Stem Cell, Rajamani et al. (2018) devise a new, efficient method to differentiate iPSCs from super-obese and normal donors into iHTNS and investigate their different molecular profiles and hormone responses.
Medical subject headings
- Induced Pluripotent Stem Cells